World’s first new blood group “CRIB”: Karnataka woman becomes part of 2025 history

World’s first new blood group “CRIB”: Karnataka woman becomes part of history

Recently, a discovery has been made in the field of haematology that has surprised doctors and scientists. A 38-year-old woman from the Kolar district of Karnataka has been found to have a blood group that was not recorded anywhere in the world till now. This rare blood group has been identified as CRIB (Chromosome Region Identified as Blood group).

Experts say that this discovery is a historic achievement for medical science, as no such blood group had been discovered before. This woman is the first person in the world whose blood contains this special antigen.

Revealed during heart surgery

This matter came to light when the woman was admitted to R.L. Jalappa Hospital in Kolar for heart surgery. According to reports, the woman’s blood group was normally recorded as O Rh+. But when a blood transfusion was required before the operation, none of the blood units available matched her body type.

The tests were repeated several times, but each time the result was that her blood was not compatible with any normal blood group. Even the blood of family members did not match her. Given this unusual condition, her blood samples were sent to the International Blood Group Reference Laboratory (IBGRL) in Bristol, UK.

After research lasting about 10 months, scientists concluded that a completely new antigen is present in the woman’s blood, which has now been named “CRIB”.

What is CRIB?

The full form of CRIB is: Chromosome Region Identified as Blood group.

It is not like any normal blood group (such as A, B, O, AB) but is a rare antigen, which is found on the surface of red blood cells (RBCs).

CRIB is a part of the Cromer blood group system.

There are two reasons behind naming this antigen “CRIB” –

CR means Cromer System

IB is related to India and Bangalore, because this is where it was discovered.

Why was it named CRIB?

There was a long research behind this discovery. Scientists tested the woman’s blood in various laboratories around the world. Finally, the International Blood Group Reference Laboratory (IBGRL), Bristol, confirmed it.

Since this antigen is part of the Cromer blood group and was identified in Bangalore, India, it was named CRIB.

A woman is the first person in the world.

This woman is the first and only person in the world in whom this new antigen has been found. After this discovery, Rotary Bangalore TTK Blood Center, Karnataka State Blood Transfusion Council, and ICMR-Indian Institute of Immunohematology (IIH), Mumbai have jointly started a Rare Donor Registry.

The purpose of this registry is that if such a rare blood group is found in someone else in the future, then the right blood can be made available to them on time.

Autologous Transfusion: Preparation for the future

The doctors have clearly said that if this woman needs a blood transfusion in the future, then she cannot be given blood from another person. The blood of her body matches only her blood.

That’s why she has to keep her blood safe in advance. This process is called Autologous Transfusion in the language of medical science. In this, the patient himself stores his blood in advance so that the same blood can be transfused back to him in an emergency.

Official announcement at the global level

The official announcement of this discovery was made on 4 June 2025 in Milan, Italy. This information was shared at the 35th Congress of the International Society of Blood Transfusion.

At the conference, scientists said that the woman’s blood is “pan-reactive”, that is, it does not match any normal blood sample. This is why it was recorded as a new and unprecedented blood group.

Why is this discovery historic?

1. New identification – For the first time in the world, a blood group called CRIB has been discovered.

2. Future security – This will help medical science understand how wide the variations of blood groups can be.

3. Rare Donor Registry – This initiative can give life to those patients whose blood group is extremely rare.

4. New chapter in scientific research – CRIB has given a new turn to blood science.

Conclusion

The case of this woman from Karnataka is a major scientific milestone not only for India but for the entire world. It shows that there is still a lot hidden in the human body about which science has not been able to know completely.

The discovery of the CRIB blood group has proved that every human body is unique. In the coming times, this discovery can make the way easier for the treatment of patients with rare blood groups in the medical world.

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